Vaccine design

Advice on the design of vaccines, tuning of the recombinant protein expression and purification.

Our scientific staff has over 10 years of experience in the design, cloning, purification and preclinical studies of peptidic-based vaccines. We can advise the best constructions, with a complete study in silico predictive isoelectric point, hydrophobicity, D conformation and other factors involved in the type and strength of the immune response triggered by the vaccine.
In Diomune, we produce recombinant proteins at a large scale (from 30-1000 liters) in a free-protease E.coli, yeast, and baculovirus systems from a variety of vectors with different tags and/or fusion partners.